E3 Ligase Landscape
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Uniprot:
.....
Score:
....
E3 ligase source
Subcellular location
Ligandability
E3drug
E3chem
E3cova
E3dark
No ligand available
Virtual Screening - HyperAttention
Top prediction: 1
500
Top
10
predictions
&
Probability: 0.5
1
Probability
≥
0.9
Identifier
Label
E3 Ligase
Probability (0-1,1 highest)
Expression
TCGA High Expression Cancer Type:
HPA pathology High Expression Cancer Type:
GTEx High Expression Tissue:
Tabula High Expression Tissue:
PPI
GO Enrichment
KEGG Enrichment
Target
Detection Methods
PPI type
Source
Interface E3
Interface Target
High Confidence*
*High confidence mark available in text mining based PPI sources, such as BioGrid, IntAct
GO enrichment
KEGG enrichment
Structures
Probability of Essentiality via CRISPR
Probability of Essentiality via RNAi
E3 Ligase Landscape
