Welcome to PILNC
Long non-coding RNAs (lncRNAs) are pivotal regulators in cancer targeted therapies and immunotherapies. In the Pharmacogenomic and Immune Landscape of LncRNA (PILNC) study, we embarked on a thorough exploration of lncRNAs' impact on the cancer signaling pathways, drug responsiveness and tumor immune microenvironment. Moreover, our investigation revealed noteworthy correlations between lncRNAs and the efficacy and toxicity of immunotherapeutic interventions.

  • In PILNC, users can:
    • Browse or search associations between lncRNAs and cancer signaling pathways across human cancers;
    • Browse or search associations between lncRNAs and imputed drug responses across human cancers;
    • Browse or search associations between lncRNAs and immune checkpoints across human cancers;
    • Browse or search associations between lncRNAs and different types of immune cell infiltration across human cancers;
    • Browse or search lncRNAs associated with immunotherapy response;
    • Browse or search lncRNAs associated with irAE.
Browse by modules
Browse by cancer types
ACC

ACC

BLCA

BLCA

BRCA

BRCA

CESC

CESC

CHOL

CHOL

COAD

COAD

DLBC

DLBC

ESCA

ESCA

GBM

GBM

HNSC

HNSC

KICH

KICH

KIRC

KIRC

KIRP

KIRP

LAML

LAML

LGG

LGG

LIHC

LIHC

LUAD

LUAD

LUSC

LUSC

MESO

MESO

OV

OV

PAAD

PAAD

PCPG

PCPG

PRAD

PRAD

READ

READ

SARC

SARC

SKCM

SKCM

STAD

STAD

TGCT

TGCT

THCA

THCA

THYM

THYM

UCEC

UCEC

UCS

UCS

UVM

UVM