Long non-coding RNAs (lncRNAs) are pivotal regulators in cancer targeted therapies and immunotherapies. In the Pharmacogenomic and Immune Landscape of LncRNA (PILNC) study, we embarked on a thorough exploration of lncRNAs' impact on the cancer signaling pathways, drug responsiveness and tumor immune microenvironment. Moreover, our investigation revealed noteworthy correlations between lncRNAs and the efficacy and toxicity of immunotherapeutic interventions.
- In PILNC, users can:
- Browse or search associations between lncRNAs and cancer signaling pathways across human cancers;
- Browse or search associations between lncRNAs and imputed drug responses across human cancers;
- Browse or search associations between lncRNAs and immune checkpoints across human cancers;
- Browse or search associations between lncRNAs and different types of immune cell infiltration across human cancers;
- Browse or search lncRNAs associated with immunotherapy response;
- Browse or search lncRNAs associated with irAE.